Sure, it works… but is it Validated?

Validation papers for the InnoTyper 21 and InnoQuant Kits are now published! Plus third party studies demonstrating utility for forensic DNA casework.  

Validation Publications:

Development and Validation of a Novel Multiplexed DNA Analysis System, InnoTyper 21
Brown, Hiromi et al. Forensic Sci. Int. Genet. (2017) 29:80–99.

Development and Validation of InnoQuant HY, a System for Quantitation and Quality Assessment of Total Human and Male DNA Using High Copy Targets
Loftus, Andrew et al. Forensic Sci. Int. Genet. (2017) 29:205-217.

Development and validation of InnoQuant, a sensitive human DNA quantitation and degradation assessment method for forensic samples using high copy number mobile elements Alu and SVA
Pineda, Gina M. et al. Forensic Sci. Int. Genet. (2014), 13: 224 - 235

Third Party Studies Demonstrating Utility:

Improving STR Profile Success Rates for Property Crime Specimens using InnoQuant Human DNA Quantification & Degradation Assessment Kit
LeFebvre, AK, et al. J Forensic Investigation (2017) 5(2): 8.

Successful Nuclear DNA Profiling of Rootless Hair Shafts: A novel approach
Grisedale, Kelly et al. Int J Legal Med DOI: 10.1007/s00414-017-1698-z

Analysis of DNA from Post-blast Pipe Bomb Fragments for Identification and Determination of Ancestry
Tasker, Esiri et al. Forensic Sci. Int. Genet. (2017) 28:195-202.

Evaluation of the InnoTyper 21 Genotyping Kit in Multi-ethnic Populations
Ristow, Peter Gustav et al. Forensic Sci. Int. Genet. (2017) 30:43-50.

Evaluation of InnoTyper 21 in a Sample of Rio de Janeiro Population as an Alternative Forensic Panel
Moura-Neto, R.S., Mello, I.C.T., Silva, R. et al. Int J Legal Med (2017).

DNA and RNA Profiling of Excavated Human Remains with Varying Postmortem Intervals
van den Berge, M. et al. Int J Legal Med (2016) 130: 1471.

Examination of 20 Retrotransposable Polymorphic Insertion/Null (INNUL) markers for their utility in kinship testing using a commercial software program (LSAM)
AnniLauri Villeme, Gretchen Bartizal, Carolyn R. Steffen, Michael D. Coble. Poster Presentation at AAFS Annual Meeting, Las Vegas, NV, February 26, 2016


“We have seen the power of both the InnoQuant and InnoTyper systems to get nuclear DNA results from very compromised samples, even those that are over 150 years old. These new technologies will help us get answers in some of our most difficult cases.”
                - Dr. Jose Lorente, Director, University of Granada Genetic Identification Laboratory in Spain

“Our studies have shown that the InnoTyper 21 kit can recover informative profiles from extremely challenging skeletal remains that have failed to yield results using other methods. We are planning to implement the system and expect it to become an important tool for us.”
                - Dr. Bruce Budowle, Director of the University of North Texas Health Science Center (UNTHSC) Center for Human Identification

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